Dr. Matteo Villa
Photo: Marcus Rockoff
Immune cells are activated, migrate and perform their functions in tissues with different chemical and physical properties. How do immune cells adapt their behavior to the ever-changing environment that surrounds them?
With his research at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Dr. Matteo Villa will answer this question by analysing the molecular events underlying the adaptation of T cells during their migration from the lymph nodes to the intestinal environment. Using technology known as single-cell RNA sequencing, he will profile individual cells, build their “family tree” and define the steps of the environmental adaptation that allows T cells to thrive in the intestine.
Understanding the details of this process will aid the design of therapies targeted to modulate T cell function in a tissue-specific fashion.
The project of Dr. Matteo Villa is supported by the “Young Investigator Fund for Innovative Research Ideas” of the Schering Stiftung and the Fritz Thyssen Foundation.Share this post
Matteo Villa studied Biotechnology at the University of Milano-Bicocca, Italy. His PhD studies were funded by a Boehringer Ingelheim Fonds PhD fellowship and were performed at the MRC National Institute for Medical Research in London, UK, under the supervision of Dr. Gitta Stockinger. Since 2016, Matteo Villa is a postdoctoral fellow of the Alexander von Humboldt Stiftung and he works at the Max Planck Institute of Immunobiology and Epigenetic, in Freiburg, in the lab of Dr. Erika Pearce.
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