Jenna Sutela, "HMO nutrix", 2022, various materials. Exhibition view, Schering Stiftung, 2022.
Photo: Jens Ziehe
November 08, 2022, 6 p.m.
Lecture in German.
Please register via the online-form (see below).
For more than 150 years, people have been searching for a substitute food similar to breast milk to improve the health of non-breastfed infants. Human milk oligosaccharides (so-called HMOs), complex sugars that make up the third largest fraction of milk by volume, have also received considerable attention, particularly as a factor influencing bacterial colonization of the infant gut. More and more functions are being discussed for the numerous HMOs, of which well over 100 different structures have been identified. They are considered anti-inflammatory, anti-infective and are even said to positively influence brain development. For some years now, it has been possible to produce individual representatives of the HMOs synthetically in larger quantities, making clinical studies possible for the first time. They are also already being added to infant milk formula. However, since the individual composition of HMOs is very different, the lecture will discuss whether and to what extent the complex system of these structures and their interactions with various microorganisms in humans and their immune systems can be generally imitated for all infants.Share this post
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Silvia Rudloff studied nutritional sciences in Bonn and obtained her doctorate in infant nutrition at the Department of Nutrition at the University of California in Davis (USA). The subsequent years at the Research Institute of Child Nutrition in Dortmund, Germany, shaped her work on human milk oligosaccharides to this day, as at that time it was already possible to conduct studies on the metabolism of these breast milk components in premature infants. Today, Silvia Rudloff is Professor of Nutritional Physiology, teaches in her special field of infant and child nutrition, and is a member of the Nutrition Commission of the German Society for Pediatrics and Adolescent Medicine. On the one hand, she conducts research at the University Children's Hospital and the Institute of Nutritional Science at the Justus Liebig University Giessen as head of the method platform 'Stable Isotopes and Cell Biology'. Her current research field includes effects of milk oligosaccharides on the gut-microbiota-brain axis as well as metabolic and functional aspects of other bioactive substances in food.Close
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