Prof. Dr. Frances Arnold
November 11, 2016, 4–6 p.m.
This years Bohlmann Lecture entitled “Innovating with Evolution: Expanding the Enzyme Universe,” will be presented by Prof. Dr. Frances Arnold of the California Institute of Technology in Pasadena, California, USA
Frances Arnold’s research focuses on protein engineering by directed evolution, with applications in alternative energy, chemicals, and medicine. Dr. Arnold pioneered the ‘directed evolution’ of proteins, mimicking Darwinian evolution in the laboratory to engineer proteins with new and useful properties.
“Nature makes a stunning array of molecules and materials using spectacular catalysts that you can literally scrape from the bottom of your shoe. But chemists make, and dream of, many more that are not known in biology. We would love to be able to program biological systems — e.g. clean and efficient microbial factories — to make some of these molecules and materials, but that will require new biological catalysts. Not satisfied with nature’s vast catalytic repertoire, we want to create new enzymes and expand the range of genetically encoded chemistry. I will describe how we can use the most powerful algorithm for biological design, evolution, to optimize existing enzymes and invent new ones. Mimicking nature’s evolutionary tricks and using a little chemical intuition, we can generate whole new enzyme families that catalyze important reactions not (yet) known in nature, thereby expanding the chemistry of the biological world and the molecules and materials we can build.”
The Schering Stiftung supports the Bohlmann Lecture in order to strengthen the international networking of scientists and to make renowned experts visible as role models for young scientists. Moreover, the Lecture makes it possible for a broader public to learn about the latest scientific findings.
The lecture will be followed by the award ceremony of the Schering Prize 2015. The 5,000-euro prize is given for outstanding dissertations in chemistry and is also funded by the Schering Stiftung. This year’s prize winner is Dr. Stephan Warnke.
Dr. Warnke from the Institute for Chemistry and Biochemistry at Freie Universität Berlin is awarded the Schering Prize 2015 for his research on "A Gas-Phase Approach to Biomolecular Structure".Learn more
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